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Stereoselective cyclization of α-alkoxyallylstannane alkynals and their Co-complexes. A new route to cyclododecyne-1,2-diol derivatives

✍ Scribed by James A. Marshall; Wei Yi Gung


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
280 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis


The a-alkoxyallylstannane dicobalt hexacarbonyl alkynal complex 18 afforded the cyclododecadienyne alcohol complex 19 as a single diastereoisomer in 70% yield upon treatment with BF3 l Et20 at -78°C. The reaction is thought to proceed by prior isomerization to the y-alkoxyallylstannane.