Treatment of stereodefined w-halo-2-iodoalkene derivatives (l), prepared via stereoselective addition reactions of alkynes, with either n\_BuLi (1 equiv) or t-BuLi (2 equiv) can produce exccyclic alkenes whose isomeric purity is essentially 100%.
โฆ LIBER โฆ
Stereoselective cyclic carbolithiation of alkyne derivatives. A stereoselective synthesis of exocyclic alkenes
โ Scribed by Guangzhong Wu; Fredrick E Cederbaum; Ei-ichi Negishi
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 240 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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