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Stereoselective binding of the glucuronide of ketoprofen enantiomers to human serum albumin

✍ Scribed by Nathalie Dubois; Françoise Lapicque; Jacques Magdalou; Michel Abiteboul; Patrick Netter

Book ID
115784065
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
668 KB
Volume
48
Category
Article
ISSN
0006-2952

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Stereoselectivity and enantiomer-enantiomer interactions in the binding of ibuprofen to human serum albumin
✍ Tomoo Itoh; Yoshikazu Saura; Yasuyuki Tsuda; Hideo Yamada 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 2 views

Binding of ibuprofen (IB) enantiomers to human serum albumin (HSA) was studied using a chiral fluorescent derivatizing reagent, which enabled the measurement of IB enantiomers at a concentration as low 5 x 10(-8) M. Scatchard analyses revealed that there were two classes of binding sites for both en