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Stereoselective binding of a 2,3-benzodiazepine to human serum albumin: Effect of conformation on tofizopam binding

✍ Scribed by Miklós Simonyi; Ilona Fitos

Book ID
115776721
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
372 KB
Volume
32
Category
Article
ISSN
0006-2952

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The role of configuration and conformati
The role of configuration and conformation in the binding of 2,3-benzodiazepines to human serum albumin
✍ Julia Visy; Miklós Simonyi 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 418 KB 👁 1 views

2,3-Benzodiazepines containing a centre of asymmetry at C-5 possess both central and helical chiralities, and the solution of their racemates contains four molecular species. The binding of these compounds to human serum albumin (HSA) was studied by affinity chromatography. The binding strength depe