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Stereoselective aza-Diels—Alder Reactions

✍ Scribed by Gerald B. Rowland; Emily B. Rowland; Qiang Zhang; Jon C. Antilla


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Inter- and intramolecular hetero diels-a
✍ Tietze, Lutz F. ;Utecht, Jens 📂 Article 📅 1992 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 542 KB

Azabutadienes f Isoxazoles f Tetrahydropyridines 1 Diels-Alder reactions / Sequential transformations Condensation of aldehydes 1 ae with 5-amino-3-methylisoxazole (4) gives the corresponding imines 5a-e with a 2-aza-1,3-butadiene moiety, which cyclize selctively, e.g. 5a to form the trans-fused tet