Stereoselective amination of chiral enolates: Synthesis of chiral key intermediates for β-lactam antibiotics
✍ Scribed by Carlos Cativiela; María D. Díaz-de-Villegas; José A. Galvéz
- Book ID
- 108036221
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 276 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
Chemical asymmetric syntheses of the key intermediates (4,6,8) for the \_\_ synthesis of monobactam antibiotics ( SQ 26776 (azthreonam), sulfazecin, and SQ 26180 ) are accomplished from I\*)-4-phenylsulfonyl-2-azetidinone. Recently much attention have been focused on the nonclassical B-lactam antibi
## Abstract The importance of the β‐lactam substructure is exemplified by the several classes of β‐lactam antibiotics. Among the synthetic routes available to obtain this interesting scaffold, the Kinugasa reaction is a convergent strategy. In this article, the synthesis of a variety of chiral β‐la