𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereoselective Alkylation of N -Boc-protected-5-substituted δ-Lactams: Synthesis of α ,δ-Disubstituted δ-Amino Acids

✍ Scribed by Casimir, J. Richard; Didierjean, Claude; Aubry, André; Rodriguez, Marc; Briand, Jean-Paul; Guichard, Gilles

Book ID
117992846
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
82 KB
Volume
2
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereoselective Synthesis of Some γ- and
Stereoselective Synthesis of Some γ- and δ-Fluoro-α-amino Acids
✍ Kröger, Stefan ;Haufe, Günter 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 705 KB

## Abstract (__R__)‐(−)‐2‐Amino‐4‐fluorobutyric acid (4c) (32% ee) and six of its homologues 9 have been synthesized by diastereoselective alkylation (54–72% yield) of (__R__)‐(+)‐camphor‐based glycine ester imines 1 with 1‐bromo‐2‐fluoro‐alkanes 6, at low temperature, followed by deprotection. Sim

N-Boc-α-tosylsarcosine ethyl ester: An α
N-Boc-α-tosylsarcosine ethyl ester: An α-amido sulfone for the regio- and stereoselective synthesis of protected γ,δ-unsaturated N-methyl-α-amino acids by palladium-catalyzed nucleophilic substitution
✍ Diego A. Alonso; Ana Costa; Carmen Nájera 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 176 KB

N-Boc-u-msylsarcosine ethyl ester (3) reacts under neutral conditions either with allylic carbonates or with vinyloxinme in the presence of a catalytic amount of Pd(PPh3) 4 and dppe (5 mol%) to give regio-and stereoselectively the corresponding allylated products $ and 6, respectively. Reductive des

Synthesis of γ,δ-unsaturated 6-hydroxy s
Synthesis of γ,δ-unsaturated 6-hydroxy substituted α-amino acids by palladium-catalyzed alkylation of monoepoxydienes
✍ Angel Mazón; Carmen Nájera; Jesús Ezquerra; Concepción Pedregal 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 215 KB

Monoepoxydienes 1, derived from =cyclic and cyclic conjugated dienes, react under neutral conditions with the benzophenone imin¢ of 81ycine nitrile 4 in the presence of a catalytic amount of Pd(PPh3)4 (5% mol) to afford the cou~pondin8 unsaturated 6-hydroxy substituted ct-amino acids S in a regio (1