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Stereoselective aldol condensations via boron enolates

โœ Scribed by Evans, D. A.; Vogel, E.; Nelson, J. V.


Book ID
121459154
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
440 KB
Volume
101
Category
Article
ISSN
0002-7863

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โœ Ian Paterson; Cynthia K McClure ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 341 KB

A/do/ condensation of chiraal ethylketones 8 and 9,via their 9-BBN or "BupB eno/ates,with methacrolein and acetaldehyde gives mainly the &&&I adduct, 8 -+ 14 or 9 + 18. The chiral reagent (+)-(lpc)~OTf, in the presence of EL& is used to enhance the formation of 14 and 78, while