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Stereologic analysis of vulnerable neocortical neurons in normal aging and Alzheimer's disease

✍ Scribed by Thierry Bussiere; Bridget A. Wicinski; Grace I. Lin; Daniel P. Perl; Peter Davies; Ralph A. Nixon; John H. Morrison; Patrick R. Hof


Book ID
117411935
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
377 KB
Volume
21
Category
Article
ISSN
0197-4580

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This article reviews the possible relationships between the localization of cellular pathologic changes in Alzheimer's disease (AD), and the distribution of neuronal components of the neocortical circuitry that are affected by these alterations. In particular, evidence from the study of large autops