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Stereoisomeric flavor compounds. Part LXV: Preparative resolution of the enantiomers of chiral dihydrofuranones by recycling chromatography

✍ Scribed by Bruche, Günther ;Mosandl, Armin ;Kinkel, Joachim N.


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
282 KB
Volume
16
Category
Article
ISSN
0935-6304

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✦ Synopsis


Abstract

Preparative resolution of the enantiomers of several chiral dihydrofuranones, known to be important flavor compounds, has been achieved by combining the use of bonded β‐cyclo‐dextrin as chiral stationary phase with closed‐loop recycling chromatography. The purity of the separated enantiomers has been determined by chirospecific capillary GC analysis, using heptakis(2,3‐di‐O‐methyl‐6‐TBDMS)‐β‐cyclodextrin as the chiral stationary phase.