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Stereocontrolled Total Synthesis of (-)-Callipeltoside A.

โœ Scribed by Ian Paterson; Robert D. M. Davies; Annekatrin C. Heimann; Rodolfo Marquez; Arndt Meyer

Publisher
John Wiley and Sons
Year
2004
Weight
84 KB
Volume
35
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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The callipeltosides were isolated by Minale and co-workers from the shallow-water lithistid sponge Callipelta sp., collected off the east coast of New Caledonia. [1a,b] Callipeltoside A (1 in Scheme 1, obtained in 1.4 ร‚ 10 ร€4 % yield) was found to inhibit in vitro the proliferation of KB and P388 ce