Stereocontrolled synthesis of β-C-glycosides and amino β-C-glycosides by Wittig olefination of perbenzylated glyconolactones derivatives
✍ Scribed by Adeline Molina; Stanislas Czernecki; Juan Xie
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 166 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Wiuig olefination of perbenzylated glyconolactones afforded stereoselectively the Z-C-glycosylidenes which were transformed to the corresponding ~-C-glycosides and amino ~-Cglycosides by hydrogenation followed by acetylation.
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## Abstract For Abstract see ChemInform Abstract in Full Text.
C-Glycosyl compounds represent a class of products used as chiral synthons' and as potential glycosidase inhibitors'. A number of methods have been devised for their synthesis3, but despite the biological importance of D-glucosamine, few C-glycosyl derivatives of this carbohydrate have been synthesi