✦ LIBER ✦

Stereocontrolled synthesis of retinoids functionalized at C-13 by suzuki coupling reactions

✍ Scribed by Rosana Alvarez; Beatriz Iglesias; Angel R. de Lera

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 923 KB
Volume: 55
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(99)00861-3

No coin nor oath required. For personal study only.

✦ Synopsis

The retinal analogues ( 13Z)-13-bromo-13-desmethylretinal (3) and ( 13E)-20,20,20-trifluororetinal (4) have been efficiently synthesized using the palladium-catalyzed cross-coupling of boronic acid 8 and electrophiles 9 and 10, respectively. For the first analogue, the coupling of 8 and the gem-dibromide 9 took place with high stereoselectivity.

The configuration of the C13-Cl4 double bond in 4 relied on the stereoselective preparation and coupling of alkenyltriflate Z-10 from P-ketoester 15.

📜 SIMILAR VOLUMES

ChemInform Abstract: Stereocontrolled Sy

ChemInform Abstract: Stereocontrolled Synthesis of Retinoids Functionalized at C-13 by Suzuki Coupling Reactions.

✍ Rosana Alvarez; Beatriz Iglesias; Angel R. de Lera 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

Synthesis of 11C-/13C-Ketones by Suzuki

Synthesis of 11C-/13C-Ketones by Suzuki Coupling

✍ Obaidur Rahman; Tor Kihlberg; Bengt Långström 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB

Synthesis of New Pyridazino[4,5-c]isoqui

Synthesis of New Pyridazino[4,5-c]isoquinolinones by Suzuki Cross-Coupling Reaction.

✍ Zsuzsanna Riedl; Bert U. W. Maes; Katrien Monsieurs; Guy L. F. Lemiere; Peter Ma 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Synthesis of C3-Symmetric Nano-Sized Pol

Synthesis of C3-Symmetric Nano-Sized Polyaromatic Compounds by Trimerization and Suzuki—Miyaura Cross-Coupling Reactions.

✍ Sambasivarao Kotha; Dhurke Kashinath; Kakali Lahiri; Raghavan B. Sunoj 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 176 KB 👁 1 views

Synthesis of C3-Symmetric Nano-Sized Pol

Synthesis of C3-Symmetric Nano-Sized Polyaromatic Compounds by Trimerization and Suzuki−Miyaura Cross-Coupling Reactions

✍ Sambasivarao Kotha; Dhurke Kashinath; Kakali Lahiri; Raghavan B. Sunoj 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 236 KB 👁 1 views

ChemInform Abstract: Stereocontrolled Sy

ChemInform Abstract: Stereocontrolled Synthesis of 13-Substituted Retinoic Acids by Palladium-Catalyzed Coupling Reaction of Alkenyl Stannane with Vinyl Triflate.

✍ Akimori Wada; Kouki Fukunaga; Masayoshi Ito 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v