Stereocontrolled Formation of Three Contiguous Stereogenic Centers by Free Radical Cyclization — Synthesis of (+)-Iridomyrmecin and (-)-Isoiridomyrmecin — Formal Synthesis of δ-Skythantine

Stereocontrolled Formation of Three Cont

Stereocontrolled Formation of Three Contiguous Stereogenic Centers by Free Radical Cyclization – Synthesis of (+)-Iridomyrmecin and (–)-Iso-iridomyrmecin – Formal Synthesis of δ-Skythantine

✍ Bernd Schöllhorn; Johann Mulzer 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB

## Abstract A synthesis of (__+__)‐iridomyrmecin (**1**), a naturally occurring insecticide with antibiotic properties, via free radical cyclization is described. In this key step, three contiguous stereogenic centers are generated with a high level of stereocontrol. (© Wiley‐VCH Verlag GmbH & Co.