Stereochemisty of 3,3-disubstituted 2-methoxy-1,2-oxazolidines
โ Scribed by Remir G. Kostyanovsky; Volker Schurig; Konstantin A. Lyssenko; Oliver Trapp; Gulnara K. Kadorkina; Vasily R. Kostyanovsky; Boris B. Averkiev
- Book ID
- 111730501
- Publisher
- Royal Society of Chemistry
- Year
- 2004
- Tongue
- English
- Weight
- 339 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0959-9436
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๐ SIMILAR VOLUMES
A versatile method for the solid phase synthesis of oxazolidin-2-ones is described. A resin bound phenolic group was treated with (ยฑ)-epichlorohydrin followed by opening of the epoxide ring with sodium azide. The resulting 1-azido-3-aryloxypropan-2-ol was treated with p-nitrophenylchloroformate and
## 2S,4R~R)-2-Met~~~-~~~l-3-(4-merhylbe~enesu~onyl)-5-phenyl-l 3-oxazolidine (2~) ad& trimethylsilyl I-cycloalkenyl ethers under L.ewis acid catalysis with complete induced and high simple &astereoselectivi@ to yield homochiral oxazolidine-m&ed 2-formylalknnones. Key words: 2-