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Stereochemistry of the 5-(p-aminophenyl)-1,2,3,4-tetrahydroxypentane portion of methanopterin

โœ Scribed by White, Robert H.


Book ID
126150689
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
301 KB
Volume
108
Category
Article
ISSN
0002-7863

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Biosynthesis of 5-(p-aminophenyl)-1,2,3,
โœ Robert H. White ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Springer ๐ŸŒ English โš– 561 KB

The biosynthesis of the 5-(p-aminophenyl)-l,2,3,4tetrahydroxypentane moiety of methanopterin was studied in methanogenic bacteria. By comparing the extent of deuteration of the benzyl group of 5-(p-aminophenyl)-1,2,3,4-tetrahydroxypentane with the benzyl group of phenylalanine isolated from cells gr

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## Abstract __cis__โ€ and __trans__โ€(3,6โ€D~2~)โ€1,4โ€cyclohexadienes **1a** and **1b** have been synthesized from __cis__โ€3,4โ€dichlorocyclobutene (5). Aromatization to benzene with DDQ is __cis__โ€stereospecific with an uncertainty of 5%. This result is discussed in relation to concerted or stepwise me