Stereochemistry of reduction of cyclic ketones by alkali metals and by sodium dithionite.

✍ Scribed by Graziano Castaldi; Giulio Perdoncin; Claudio Giordano; Francesco Minisci

• Publisher: Elsevier Science
• Year: 1983
• Tongue: French
• Weight: 243 KB
• Volume: 24
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)81962-0

✦ Synopsis

Surmary: An opposite stereoselectivity is observed in the r&cticn of 3d-hydroxy-5j%7-oxo-cholaic acid by alkali notals and by sodiun dithicnite, ccntraty to the results reported' with other cyclic or bicyclic ketones. An electrartrznsfer mechanism follmed by coupling of the ketyl radical with SOI is suggested for the r&cticn by sodiun dithionite.