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Stereochemistry of hydride reductions. The tricyclo[9.3.1.0.3,8]pentadecane (taxane) ring system

✍ Scribed by K.J. Shea; Richard G. Higby; Jeffrey W. Gilman

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
253 KB
Volume
31
Category
Article
ISSN
0040-4039

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## Abstract The feasibility of the titled reactions for the rapid, enantioselective synthesis of __cis__‐tricyclo[9.3.1.0^3,8^]pentadecane precursors to taxusin and taxol has been examined. The catalysts most well suited to inducing the appropriate 1,2‐shifts have been identified. To a great extent