Stereochemistry of diastereomeric neolignans from Piper hookeri by nuclear magnetic resonance spectroscopy

✍ Scribed by Padmanava Pradhan; Asoke Banerji

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 107 KB
• Volume: 9
• Category: Article
• ISSN: 0958-0344
• DOI: 10.1002/(sici)1099-1565(199803/04)9:2<71::aid-pca390>3.0.co;2-0

✦ Synopsis

A new 8.1' type neolignan, (8R,1'S or 8S,1'R)-4-[2-(1,3-benzodioxolo-5-yl)-1-methylethyl]-2,5-dimethoxy-1propenyl-2,5-cyclohexadienone, hookerinone B a diastereomer of hookerinone A, and a pair of 8.3' type diastereomeric neolignans, lancifolin C and lancifolin D, were isolated from the alchoholic extracts of the medicinal plant Piper hookeri. The absolute configurations of these neolignans and of a third diastereomeric pair, dihydroisofutoquinol A and dihydroisofutoquinol B, were established by nuclear magnetic resonance spectroscopic methods.