Stereochemistry of decarbalkoxylation of arylmethylene-propanedioic acids dimethyl esters
β Scribed by Angela M. Bernard; P.Paolo Piras; Adriana Serra
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 94 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Halide ions increase the rate of decarbalkoxylation of arylnethylene-propanedioic acids dimethyl esters.
π SIMILAR VOLUMES
Recently Krapcho and Lovey have reported that germinal diesters, B-keto esters and a-cyano esters undergo decarbalkoxylatlons when heated with sodium chloride In wet dimethyl eulfoxide at temperatures of 140-185' (1). We now wish to report further experiments addressed to the question of whether add
N-(AtylmelhyIene)dehydmalanine methyl esters undergo a stereoregulated dimerizotion maelion lo produce hetewlic a, a'-diaminodica&qIic acid derivatives. Further transfomration yielak stable hydnxhlokies of free a, a'-diaminodica&axylic acids which represent either substihlled 3-amino-piperidne-3,kii