Stereochemistry of cyclopentane derivatives from 2, 3JCH dependence on dihedral angle (θ HCCX)
✍ Scribed by Valdemar Lacerda Jr; Gil V. J. da Silva; Mauricio G. Constantino; Reginaldo B. dos Santos; Eustáquio V. R. de Castro; Renzo C. Silva
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 154 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2182
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✦ Synopsis
Abstract
The ^2, 3^J~CH~ dependence on dihedral angle (θ HCCX) for cyclopentane derivatives was investigated. We observed that the combined use of experimentally obtained ^2, 3^J~CH~ values and the theoretically determined dihedral angles between the corresponding nuclei can be used to infer the relative stereochemistry of the ring substituents in cyclopentane derivatives. There is a good correlation between the magnitude of ^3^J~CH~ and the dihedral angle between the hydrogen and the coupled carbon (R^2^ = 0.88). Copyright © 2008 John Wiley & Sons, Ltd.