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Stereochemistry and 13C NMR investigation of 9-halotetrahydro-4H-pyrido[1,2-a]pyrimidin-4-ones

✍ Scribed by Gábor Tóth; István Hermecz; Tibor Breining; Zoltán Mészáros; István Bitter


Book ID
112127097
Publisher
Journal of Heterocyclic Chemistry
Year
1983
Tongue
English
Weight
244 KB
Volume
20
Category
Article
ISSN
0022-152X

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Several 6-methyl-9-carbamoyltetrahydro-4H-pyrido[l,2-a]pyrimid~-4-ones have been prepared using phosgene iminium chloride. These compounds can exist in equilibrium as the cis (3A) imine$(3B) enaminee trans (3C) imine. 'H, 13C and "N NMR prove that the cis-and trans-imine isomers are predominant in t