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Stereochemically controlled synthesis of spirocyclic lactones and ethers from N-methyl-4-piperidone and 3-quinuclidinone by phenylthio migration

✍ Scribed by Iain Coldham; Eric W. Collington; Peter Hallett; Stuart Warren


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
196 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


Phenylthio migration coupled to stereoselective aldol reactions provides single diastereoisomers of allylic sulphides and spirocyclic tetrahydrofurans and butenolides based on the piperidine and quinuclidine skeletons.