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Stereochemical Relay via Axially Chiral Styrenes: Asymmetric Synthesis of the Antibiotic TAN-1085

โœ Scribed by Keiji Mori; Ken Ohmori; Keisuke Suzuki

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
591 KB
Volume
48
Category
Article
ISSN
0044-8249

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๐Ÿ“œ SIMILAR VOLUMES

Nonconventional Stereochemical Issues in
Nonconventional Stereochemical Issues in the Design of the Synthesis of the Vancomycin Antibiotics: Challenges Imposed by Axial and Nonplanar Chiral Elements in the Heptapeptide Aglycons
โœ David A. Evans; Christopher J. Dinsmore; Paul S. Watson; Michael R. Wood; Timoth ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 185 KB

Controlling the elements of planar and axial chirality are the principal challenges in the synthesis of the aglycon of vancomycin. Vancomycin is the prototypical member of the glycopeptide family of antibiotics which are effective for the treatment of infections by methicillin-resistant Staphylococc