✦ LIBER ✦

Stereochemical differentiation of cyclic glycols by ion-molecule reactions in a quadrupole mass spectrometer using dimethyl ether acetonitrile and 2-S-pyrrolidinemethanol

✍ Scribed by Valerie Mancel; Nicole Sellier

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 94 KB
Volume: 14
Category: Article
ISSN: 0951-4198
DOI: 10.1002/(sici)1097-0231(20000130)14:2<80::aid-rcm838>3.0.co;2-8

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✦ Synopsis

In this study, ion-molecule reactions using chemical ionization in the positive ion mode using dimethyl ether, acetonitrile and 2-S-pyrrolidinemethanol as reagent gases have been used to distinguish between cis-and trans-1,2-cyclopentanediol and cis-and trans-1,2-cyclohexanediol. In the gas phase, the stereospecific ionmolecule reaction gives characteristic ions and substantial differences are observed in their relative abundances from which the diastereoisomers of those cyclic glycols can be clearly differentiated.