Stereoarrays with an All-Carbon Quaternary Center: Diastereoselective Desymmetrization of Prochiral Malonaldehydes

✍ Scribed by Dr. Bruno Linclau; Elena Cini; Catherine S. Oakes; Dr. Solen Josse; Dr. Mark Light; Dr. Victoria Ironmonger

• Book ID: 101573136
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 490 KB
• Volume: 51
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.201107370

✦ Synopsis

Ironmonger GlaxoSmithKline Old Powder Mills, Leigh, Nr Tonbridge, TN11 9AN (UK) [**] E.C. thanks Prof. M. Taddei and ERASMUS for funding. S.J. thanks NV Tibotec (Belgium) for funding. C.S.O. thanks the EPSRC, AstraZeneca, GlaxoSmithKline, and Pfizer (Organic Synthesis studentship scheme) for funding. We are grateful to Nathan Bartlett for DFT calculations, and to Dr. Karl Cable (GSK) and Dr. Andrew Gordon (GSK) for helpful discussions.