Stereo- and regioselective ring opening of alkenyl aziridines with metal halides

✍ Scribed by Giuliana Righi; Claudia Potini; Paolo Bovicelli

• Book ID: 104251523
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 138 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01118-8

✦ Synopsis

The reaction of N-Boc-alkenyl aziridines with lithium halides in presence of Amberlyst 15 afforded the stereo-and regioselective ring-opened products in high yields. The following treatment of the bromo-and iododerivatives with silica gel produced the corresponding oxazolidin-2-ones.