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Stereo- and enantioselective reactions. Application to the synthesis of biologically active compounds

✍ Scribed by Janine Cossy; Samir BouzBouz; Matthew Popkin


Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
205 KB
Volume
6
Category
Article
ISSN
1631-0748

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## Abstract The rationalization of the synthesis of substituted analogs of megazol, a biologically active 5‐nitroimidazole at position 4 of the imidazole ring, had led to the study of intermediate steps. The methylation by diazomethane of 2,4‐(5)dihalogeno‐5‐(4)nitroimidazole is regioselective lead