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Sterculic Acid and its Halphen Reaction

✍ Scribed by FAURE, P. K.


Book ID
109590420
Publisher
Nature Publishing Group
Year
1956
Tongue
English
Weight
236 KB
Volume
178
Category
Article
ISSN
0028-0836

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Microsynthesis of 3H-sterculic acid with
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## Abstract Copper‐catalysed addition of ethyl diazoacetate to methyl scearolate (20 mmol scale) and subsequent saponification gave 9, 10‐carboxymethylene, 9‐octadecenoic acid in 67% yield. The letter was decarbonylated by treatment with HClO~4~/Ac~2~O in the cold (76 ΞΌmol scale) to give cycloprope