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Stepwise Solid-Phase Synthesis and Spontaneous Homodimerization of the Helix-Loop-Helix Protein Id3

✍ Scribed by Jaroslava Svobodová; Chiara Cabrele


Book ID
101819146
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
113 KB
Volume
7
Category
Article
ISSN
1439-4227

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Synthesis and conformation of an analog
✍ Michael Beisswenger; Taku Yoshiya; Yoshiaki Kiso; Chiara Cabrele 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 258 KB

## Abstract Synthetic peptides reproducing the helix‐loop‐helix (HLH) domains of the Id proteins fold into highly stable helix bundles upon self‐association. Recently, we have shown that the replacement of the dipeptide Val‐Ser at the loop–helix‐2 junction with the corresponding __O__‐acyl iso‐dipe