✦ LIBER ✦

Stem cells as screening tools in drug discovery

✍ Scribed by John D McNeish

Book ID: 116383570
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 236 KB
Volume: 7
Category: Article
ISSN: 1471-4892
DOI: 10.1016/j.coph.2007.06.005

No coin nor oath required. For personal study only.

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## Abstract Mutational activation of RAS proteins occurs in nearly 30% of all human tumors. To date direct pharmacological inhibition of RAS oncoproteins has not been possible. As a consequence, current strategies are focusing on the development of inhibitors that target those kinases acting downst