Stem cell transplantation for treatment of severe autoimmune diseases: current status and future perspectives
✍ Scribed by Jantunen, E; Myllykangas-Luosujärvi, R
- Book ID
- 110012387
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 59 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0007-1188
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Motor neuron degeneration leading to muscle atrophy and death is a pathological hallmark of disorders, such as amyotrophic lateral sclerosis or spinal muscular atrophy. No effective treatment is available for these devastating diseases. At present, cell-based therapies targeting motor neuron replace
## Abstract Human bone marrow derived‐mesenchymal (skeletal) stem (MSC) cells are a group of non‐hematopoietic stem cells residing in the perivascular niches in bone marrow. These cells have the capacity to differentiate mainly into mesoderm‐type cells such as osteoblasts, chondrocytes and adipocyt