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Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

✍ Scribed by C E Hoei-Hansen; K Almstrup; J E Nielsen; S Brask Sonne; N Graem; N E Skakkebaek; H Leffers; E Rajpert-De Meyts


Book ID
108779944
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
1004 KB
Volume
47
Category
Article
ISSN
0309-0167

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## Abstract Human embryonic stem (hES) cells are typically maintained on mouse embryonic fibroblast (MEF) feeders or with MEF‐conditioned medium. However, these xenosupport systems greatly limit the therapeutic applications of hES cells because of the risk of cross‐transfer of animal pathogens. The