Stem Cell Plasticity, Beyond Alchemy
β Scribed by Michael S. Rutenberg; Takashi Hamazaki; Amar M. Singh; Naohiro Terada
- Book ID
- 105675858
- Publisher
- Carden Jennings Publishing
- Year
- 2004
- Tongue
- English
- Weight
- 93 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0925-5710
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract One of the most contentious issues in biology today concerns the existence of stem cell plasticity. The term βplasticityβ refers to the capacity of tissueβderived stem cells to exhibit a phenotypic potential that extends beyond the differentiated cell phenotypes of their resident tissue
Traditional concepts indicate that stem cells give rise to progenitor cells in a hierarchical system. We studied murine engraftable stem cells (ESCs) and progenitors in in vitro and found that ESC and progenitors exist in a reversible continuum, rather then a hierarchy. B6.SJL and BALB/c marrow cell