𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stem Cell Plasticity, Beyond Alchemy

✍ Scribed by Michael S. Rutenberg; Takashi Hamazaki; Amar M. Singh; Naohiro Terada


Book ID
105675858
Publisher
Carden Jennings Publishing
Year
2004
Tongue
English
Weight
93 KB
Volume
79
Category
Article
ISSN
0925-5710

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## Abstract One of the most contentious issues in biology today concerns the existence of stem cell plasticity. The term β€œplasticity” refers to the capacity of tissue‐derived stem cells to exhibit a phenotypic potential that extends beyond the differentiated cell phenotypes of their resident tissue

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Traditional concepts indicate that stem cells give rise to progenitor cells in a hierarchical system. We studied murine engraftable stem cells (ESCs) and progenitors in in vitro and found that ESC and progenitors exist in a reversible continuum, rather then a hierarchy. B6.SJL and BALB/c marrow cell