Stem Cell Engineering: A WTEC Global Assessment

✍ Scribed by Robert M. Nerem, Jeanne Loring, Todd C. McDevitt, Sean P. Palecek, David V. Schaffer, Peter W. Zandstra (eds.)

• Publisher: Springer International Publishing
• Year: 2014
• Tongue: English
• Leaves: 336
• Series: Science Policy Reports
• Edition: 1
• Category: Library

✦ Synopsis

This book describes a global assessment of stem cell engineering research, achieved through site visits by a panel of experts to leading institutes, followed by dedicated workshops. The assessment made clear that engineers and the engineering approach with its quantitative, system-based thinking can contribute much to the progress of stem cell research and development. The increased need for complex computational models and new, innovative technologies, such as high-throughput screening techniques, organ-on-a-chip models and in vitro tumor models require an increasing involvement of engineers and physical scientists. Additionally, this book will show that although the US is still in a leadership position in stem cell engineering, Asian countries such as Japan, China and Korea, as well as European countries like the UK, Germany, Sweden and the Netherlands are rapidly expanding their investments in the field. Strategic partnerships between countries could lead to major advances of the field and scalable expansion and differentiation of stem cells. This study was funded by the National Science Foundation (NSF), the National Institutes of Health (NIH) and the National Institute of Standards and Technology (NIST).

✦ Table of Contents

Front Matter....Pages i-xxxiii
Introduction....Pages 1-19
Physical and Engineering Principles in Stem Cell Research....Pages 21-43
High-Throughput Screening, Microfluidics, Biosensors, and Real-Time Phenotyping....Pages 45-63
Computational Modeling and Stem Cell Engineering....Pages 65-97
Stem Cell Bioprocessing and Biomanufacturing....Pages 99-117
Back Matter....Pages 119-308

✦ Subjects

Biomedical Engineering; Stem Cells; Biophysics and Biological Physics; Biochemical Engineering; Regenerative Medicine/Tissue Engineering; Medical and Radiation Physics