<p><P><STRONG>Stem Cell Biology in Health and Disease</STRONG> presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss: <BR><BR>- the
Stem Cell Biology in Health and Disease
β Scribed by Thomas Dittmar, Kurt S. ZΓ€nker (auth.), Thomas Dittmar, Kurt S. Zanker (eds.)
- Publisher
- Springer Netherlands
- Year
- 2010
- Tongue
- English
- Leaves
- 427
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss:
- the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells.
- the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs).
- the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer.
Professor Dittmar and Professor ZΓ€nker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.
β¦ Table of Contents
Front Matter....Pages i-xii
Front Matter....Pages 9-9
Introduction....Pages 1-7
Hematopoietic Stem and Progenitor Cells in Clinical Use β Transplantation and Mobilization....Pages 11-26
Ex Vivo Expansion of HSPCs....Pages 27-56
Modulation of Hematopoietic Stem/Progenitor Cell Migration....Pages 57-77
Properties of Mesenchymal Stem Cells to Consider for Cancer Cell Therapy....Pages 79-98
Front Matter....Pages 99-99
Alternative Embryonic Stem Cell Sources....Pages 101-143
Cell Therapy in Parkinsonβs Disease....Pages 145-154
Transplantation of Stem Cells and Their Derivatives in the Treatment of Multiple Sclerosis....Pages 155-181
Front Matter....Pages 183-183
Cancer: A Stem Cell-based Disease?....Pages 185-222
Stem Cell Niche Versus Cancer Stem Cell Niche β Differences and Similarities....Pages 223-233
The Chronically Inflamed Microenvironment and Cancer Stem Cells....Pages 235-250
Does the Chronically Inflamed Periodontium Harbour Cancer Stem Cells?....Pages 251-279
Leukemia Stem Cells....Pages 281-294
Cancer Stem Cells in Solid Tumors....Pages 295-326
βOne for Allβ or βAll for Oneβ? β The Necessity of Cancer Stem Cell Diversity in Metastasis Formation and Cancer Relapse....Pages 327-356
Elimination of Cancer Stem Cells....Pages 357-384
Potential Molecular Therapeutic Targets in Cancer Stem/Progenitor Cells: Are ATP-Binding Cassette Membrane Transporters Appropriate Targets to Eliminate Cancer-Initiating Cells?....Pages 385-421
Back Matter....Pages 423-426
β¦ Subjects
Cancer Research; Oncology; Stem Cells; Immunology; Transplant Surgery
π SIMILAR VOLUMES
Overview: Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of th
Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each o
<p>Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated. Beginning with the middle of the 19th cenΒ tury, our knowledge of the histological organization of
<p>The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work