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Stellettazole A: An antibacterial guanidinoimidazole alkaloid from a marine sponge Stelletta sp.

✍ Scribed by Sachiko Tsukamoto; Takahiro Yamashita; Shigeki Matsunaga; Nobuhiro Fusetani

Book ID: 104260458
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 125 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)02443-5

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✦ Synopsis

A new guanidinoimidazole alkaloid, stellettazole A (1), has been isolated from a marine sponge Stelletta sp. as an antibacterial constituent. Its structure was determined on the basis of spectral data and chemical degradation. Stellettazole A also inhibited Ca2+/calmodulin-dependent phosphodiesterase.'

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