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The Protective Effect of MK-801 on Infar

The Protective Effect of MK-801 on Infarct Development over a Period of 24 h as Assessed by Diffusion-Weighted Magnetic Resonance Imaging

✍ R. Gill; N. R. Sibson; L. Maskell; T. A. Carpenter; L. D. Hall; J. D. Pickard 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 946 KB

Diffusion-weighted MRI has been used to investigate therapeutic intervention with MK-801 in an animal model of permanent focal cerebral ischaemia. The animals were imaged continuously for 4 h and again at 24 h following occlusion of the middle cerebral artery (MCA) allowing the development of the is