creases in soluble immune factors, such as serum An imbalance between T helper cell (Th)1 and Th2interleukin-2 (IL-2) receptor have provided peripheral evilike cytokines has been described in several chronic dence that significant intrahepatic anti-HCV immune proinfectious diseases. We therefore ana
Steatosis and liver cell apoptosis in chronic hepatitis C: A mechanism for increased liver injury
β Scribed by Meagan J. Walsh; Daina M. Vanags; Andrew D. Clouston; Michelle M. Richardson; David M. Purdie; Julie R. Jonsson; Elizabeth E. Powell
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 348 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
jury. Intrahepatic viral load appears to be significantly The balance between a direct cytopathic effect by hepincreased in patients with genotype 1b. IFN-a treatment atitis C virus (HCV) and immune-mediated injury redoes significantly lower intrahepatic HCV load. (HEPAmains unclear. This report aim
To study the role of hepatitis C virus in non-A, non-B chronic hepatitis, 49 liver biopsy samples from 40 patients with non-A, non-B chronic hepatitis and 9 control patients were analyzed by complementary DNA/polymerase chain reaction. Two segments of the HCV genome, one in the nonstructural region
In livers excised for transplantation, sinusoidal endothelium appears especially vulnerable to injury during organ preservation in the cold and subsequent reperfusion. The degree of endothelial cell injury correlates with functional impairment of the graft following transplantation. The mechanism of
Tumor necrosis factor a (TNFa) has been implicated in a variety of inflammatory diseases, and anti-TNFa has been shown to improve therapy when added to standard of care in chronic hepatitis C virus (HCV) infection. In addition, patients with chronic HCV have increased serum levels of TNFa and the ma
The staging of liver fibrosis is pivotal for defining the prognosis and indications for therapy in hepatitis C. Although liver biopsy remains the gold standard, several noninvasive methods are under evaluation for clinical use. The aim of this study was to validate the recently described sequential