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Steady-State Pharmacokinetics of Roflumilast and RoflumilastN-Oxide in Patients with Mild and Moderate Liver Cirrhosis

✍ Scribed by Robert Hermann, Dr Nassr Nassr, Gezim Lahu, Éva Péterfai, Dietrich Knoerzer, Rolf Herzog, Karl Zech, Christian de Mey

Book ID
119926795
Publisher
Springer International Publishing AG
Year
2007
Tongue
English
Weight
173 KB
Volume
46
Category
Article
ISSN
0312-5963

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Pharmacokinetics of diacerein in patient
Pharmacokinetics of diacerein in patients with liver cirrhosis
✍ O. Magnard; K. Louchahi; M. Tod; O. Petitjean; P. Molinier; L. Berdah; G. Perret 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB 👁 1 views

The pharmacokinetics of diacerein following a single oral dose of 50 mg was studied in 12 healthy volunteers, 10 patients with a mild liver cirrhosis (Child Pugh's grade A), and 6 patients with a more severe liver cirrhosis (Child Pugh's grade B to C). Statistical analysis using a Kruskal-Wallis tes