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Steady-State Pharmacokinetics of Pravastatin in Children with Familial Hypercholesterolaemia

โœ Scribed by Dr Heleen E. Wiersma, Albert Wiegman, Henk D. Bakker, Richard P. Koopmans, John J.P. Kastelein, Chris J. van Boxtel


Book ID
119929901
Publisher
Springer International Publishing AG
Year
2004
Tongue
English
Weight
112 KB
Volume
24
Category
Article
ISSN
1179-1918

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โœ A.-L. Mรคkelรค; K. T. Olkkola; M. J. Mattila ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 238 KB

Ten children with rheumatoid arthritis, aged 7-16 y and weighing 20-63 kg, were treated with piroxicam mean dose 0.4 mg.kg-1 once daily for 2 weeks. On Day 15, blood was sampled from 2-120 h after the last dose. The Cmax for piroxicam ranged from 3.6 to 9.8 (mean 6.6) mg.l-1 and its half-life by log