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Steady-state levels of different tenascin mRNAs in various normal human tissues.

✍ Scribed by Laura Borsi; Barbara Carnemolla; Marco Ponassi; Luciano Zardi

Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 285 KB
Volume: 17
Category: Article
ISSN: 1065-6995
DOI: 10.1006/cbir.1993.1068

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Northern blot analysis of TN mRNA from different human tissues shows two major bands of about 6 and 8 kb which correspond to two different mRNAs generated by alternative splicing of the primary transcript. In liver, pancreas and kidney only the 6 kb TN mRNA was detectable. The highest levels of 8 kb TN mRNA were observed in placenta and skin representing 30% and 52% of total TN mRNA, respectively. In all other tissues tested the 8 kb TN mRNA represented less than 20% of total TN mRNA.

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