Staurosporine inhibition of intracellular free Ca2+ transients in mitogen-stimulated Swiss 3T3 fibroblasts
β Scribed by Richard Olsen; Deborah Melder; Markus Seewald; Robert Abraham; Garth Powis
- Book ID
- 115781500
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 660 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0006-2952
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π SIMILAR VOLUMES
Rapidly growing Swiss 3T3 fibroblasts possess a bumetanide-sensitive K + transport system that is dependent on both Na+ and CI-ions; a smaller bumetanide-insensitive component of K + transport is also present. In cells brought to the quiescent state by 8-11 days of incubation without a medium change
## Abstract Intracellular Ca^2+^ sequestration was studied by determining ^45^Ca^2+^ uptake by saponinβpermeabilized Swiss 3T3 mouse fibroblasts. Uptake was enhanced by addition of ATP and was dependent on the concentrations of ATP and saponin. ADP and UTP also enhanced uptake, but less than did AT