## Abstract The mitochondria‐mediated apoptotic pathway is regulated by members of the Bcl‐2 family. Epidermal growth factor (EGF) induces Bad phosphorylation at Ser~112~ via mitogen‐activated protein kinase (MAPK), impairing its binding to Bcl‐2 and Bcl‐xL and interfering with their anti‐apoptotic
Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms
✍ Scribed by Belmokhtar, Chafké Ahmed; Hillion, Josette; Ségal-Bendirdjian, Evelyne
- Book ID
- 110064713
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 328 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0950-9232
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