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Staurosporine directly blocks Kv1.3 channels expressed in Chinese hamster ovary cells

✍ Scribed by Jin-Sung Choi; S. J. Hahn; Duck-Joo Rhie; Yang-Hyeok Jo; Myung-Suk Kim

Publisher: Springer-Verlag
Year: 1999
Tongue: English
Weight: 83 KB
Volume: 359
Category: Article
ISSN: 0028-1298
DOI: 10.1007/pl00005350

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## Abstract An amino acid sequence variant is defined as an unintended amino acid sequence change and contributes to product heterogeneity. Recombinant monoclonal antibodies (MAbs) are primarily expressed from Chinese Hamster Ovary (CHO) cells using stably transfected production cell lines. Selecti