𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Status spongiosus in the course of treatment of malignant gliomas

✍ Scribed by Michel Poisson; Jean-Jacques Hauw; Ragay Mashaly; Charles Duyckaerts; Raymond Escourolle

Publisher
Springer US
Year
1983
Tongue
English
Weight
867 KB
Volume
1
Category
Article
ISSN
0167-594X

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✦ Synopsis

Two cases of fatal encephalopathy which appeared in the course of treatment of malignant gliomas are described. CT scan showed diffuse, low density, non-enhanced lesions of the white matter. Pathological findings showed that the CT scan aspects corresponded to status spongiosus without demyelination. We were unable to find similar reports in the literature.

In the course of treatment of malignant gliomas, diffuse, bilateral, low density CT scan changes of the white matter were attributed to radiation therapy (1, 2). They were generally presumed to be the results of diffuse demyelination, but no biopsy nor autopsy were available in such cases. We will report on two cases with pathological data.

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