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Statistical optimization of production medium for β-1,3-glucanase synthesis byTrichoderma harzianum

✍ Scribed by K. Théodore; T. Panda

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
213 KB
Volume
8
Category
Article
ISSN
0951-208X

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✦ Synopsis

Response surface methods were used to determine the optimum concentration of medium nutrients for extracellular p-1,3-glucanase production by Trichoderma harzianum in shakeflask culture. A Plackett-Burman design was used to screen the important variables which were then grouped and studied by a central composite design. The optimum levels of the medium constituents were determined by the complex algorithm of Box.

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