Statistical optimization of medium composition for aspergiolide A production by marine-derived fungusAspergillus glaucus

Sequential optimization of culture mediu

Sequential optimization of culture medium composition for extracellular lipase production by Bacillus sphaericus using statistical methods

✍ Aravindan Rajendran; Viruthagiri Thangavelu 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 348 KB

## Abstract **A** sequential optimization strategy with the aid of statistical design of experiments was used to enhance the lipase (triacylglycerol acylhydrolases, EC 3.1.1.3) production by __Bacillus sphaericus__ in submerged cultivation. A Plackett–Burman experimental design was used to evaluate