✦ LIBER ✦

Statistical decisions and the interim analyses of clinical trials

✍ Scribed by Roger Stanev

Publisher: Springer Netherlands
Year: 2011
Tongue: English
Weight: 248 KB
Volume: 32
Category: Article
ISSN: 1573-1200
DOI: 10.1007/s11017-010-9170-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Interim analyses with delayed observatio

Interim analyses with delayed observations in clinical trials

✍ Sung C. Choi; Young Jack Lee 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB 👁 2 views

The interim analyses based on group sequential procedures are not convenient if the response time relative to the patient accrual rate is long. Since in most trials patients are accrued and randomized continuously, the response data from those already randomized will continue to accumulate when a tr

Inference on Multiple Endpoints in Clini

Inference on Multiple Endpoints in Clinical Trials with Adaptive Interim Analyses

✍ Meinhard Kieser; Peter Bauer; Walter Lehmacher 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB 👁 2 views

Statistical considerations in the design

Statistical considerations in the design, conduct and analyses of antiemetic clinical trials

✍ G. R. Morrow; Enzo Ballatori; Susan Groshen; Ian Olver 📂 Article 📅 1998 🏛 Springer-Verlag 🌐 English ⚖ 30 KB

Statistical modeling of clinical intake

Statistical modeling of clinical intake decisions

✍ Richard L. Greenblatt; Benjamin Kleinmuntz 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 671 KB

Bayesian interim analysis of phase II ca

Bayesian interim analysis of phase II cancer clinical trials

✍ Daniel F. Heitjan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB 👁 2 views

Many popular sequential phase II clinical trial designs optimize some criterion subject to constraints on the error probabilities at null and alternative values of the response rate. Such designs may forfeit optimality if one fails to conduct analyses strictly according to plan. Moreover, a decision

Predictive and postdictive success of st

Predictive and postdictive success of statistical analyses of yield trials

✍ H. G. Gauch; R. W. Zobel 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 991 KB

The accuracy of a yield trial can be increased by improved experimental techniques, more replicates, or more efficient statistical analyses. The third option involves nominal fixed costs, and is therefore very attractive. The statistical analysis recommended here combines the Additive main effects a