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Statins enhance peroxisome proliferator-activated receptor γ coactivator-1α activity to regulate energy metabolism

✍ Scribed by Wenxian Wang; Chi-Wai Wong

Book ID: 105796909
Publisher: Springer
Year: 2009
Tongue: English
Weight: 304 KB
Volume: 88
Category: Article
ISSN: 0946-2716
DOI: 10.1007/s00109-009-0561-1

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## Abstract Peroxisome proliferator‐activated receptors γ coactivator‐1α (PGC‐1α) may regulate the mitochondrial antioxidant defense system under many neuropathological settings. However, the exact role of PGC‐1α in ischemic brain damage is still under debate. Based on an experimental model of tran